Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

Researchers identify the anterior insula as the brain region responsible for biasing decisions toward alcohol over social rewards in addiction.

Researchers discovered a protein that acts as a molecular switch driving cocaine addiction by altering gene activity in a brain reward circuit. The protein regulates calreticulin, which dampens neuron ...

When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, ...

CHARLESTON, South Carolina, USA, 17 December 2024 - In a comprehensive Genomic Press Interview published today in Brain Medicine, renowned neuroscientist Dr. Peter Kalivas reveals crucial insights ...

NEW YORK, NY, UNITED STATES, June 8, 2025 /EINPresswire.com/ -- Breakthrough Approach to Addiction Treatment Targets Underlying Neural Circuitry Disrupted by ...

A study published in Science Signaling on the neural circuitry mediating addiction has made significant strides, particularly in understanding the intricate mechanisms of how addictive drugs influence ...

Substance use disorders (SUDs) are a major public health concern, with opioid use disorder (OUD) and alcohol use disorder (AUD) being particularly prevalent. Recent research has explored the ...

I’ve often commented that the distance between the addiction research community and the 12-Step community polarizes treatment and undermines creative collaboration. When the professional community ...

Addiction can be a loaded term. The word originated in the 16th century to denote an abnormal attachment, typically to alcohol, and was derived from the Latin term for legally binding someone into a ...

We don’t usually think of anger and resentment the way we think about drugs or alcohol. But growing evidence suggests that, for many people, the craving for revenge follows the same patterns as ...