Use of a clinician-facing dashboard combined with a best practice alert helped increase rates of HLA-B*58:01 genetic testing among patients prescribed allopurinol.

Researchers have developed the first comprehensive atlas of allele-specific DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation. The study identified ...

The presence of the single nucleotide variation HLA-DRB1*01:03 was associated with severe ulcerative colitis, according to a Danish genome-wide association study. The association between the ...

Genes and alleles are essential to basic genetics, but what are the differences between them? In this guide, we compare genes and alleles and provide simple definitions and examples for both. Genes ...

Allele frequency is a measure of the relative frequency of an allele on a genetic locus in a population. Usually it is expressed as a proportion or a percentage. In population genetics, allele ...